In the systems biology field, there exists many different standards, with each standard serving for a different purpose. BioPax is a standard used for the representation of biological pathways. This standard has been traditionally used to describe structural and basic qualitative behavioral aspects of a biological design. While BioPax represents qualitative models, there are standards that describe quantitative models, namely the Systems Biology Markup Language (SBML). SBML is a standard for the representation of mathematical models of biological systems. SBML is built around core constructs that describe quantitative processes such as reactions. However, there are package extensions that allow for additional features. The Qualitative Models (qual) extension specifically allows SBML to describe qualitative models, which makes interconversion between both formats possible.




  • Mike Hucka