Description:

The aim of this project is is to develop a web interface for DoMo-Pred which can help to simplify the analysis of protein-protein interactions in yeast, or, if possible, in all kinds of organisms.Just upload or input pairs of protein IDs and run then the web interface will return the result and researcher can easily share the result with their colleagues and visualize the network of those interactions with significant scores. Also, the result after sort with significant scores can be used for performing other analysis.

Project details.

  • Users can upload PWMs and domain files (or use built-in data or their own trained data as well as input list of protein IDs) the application will call DoMo-Pred to analyze then return the result as a table.
  • An easy to use admin tool for change built-in dataset,like uploading more PWMs and domains and add more organisms or to remove certain PWMs and domains.
  • Sort the result by score after evaluation, then pick those interaction with significant scores (under user specified cutoff) which can be download and used to perform different analysis.
  • Use Cytoscape.JS to visualize the network of those interactions with significant scores.

Student

Long Zhang

Mentors

  • Mohamed Helmy
  • Vishwesh Kulkarni
  • Gary Bader
  • Shobhit Jain
close

2017