One of the main challenges in CBioPortal is to interpret the great amount of genomic data it has accumulated. It has currently integrated a few resources, including OncoKB, MyCancerGenome, and in the annotation column in the mutation table. In addition to this, it would be useful to link to clinical trials too for each mutation. Clinical trials are a key research tool for advancing medical knowledge and patient care. They are an important step in discovering new treatments for cancers and other diseases as well as new ways to detect, diagnose, and reduce the risk of disease. Therefore I propose to link clinical trials for cancer studies in CBioPortal which will improve the ability to analyze and interpret the genomic data for various kinds of mutations. Linking clinical trials from Molecular Match for mutations based on a patient’s cancer type and molecular data would the most feasible option for this project since it provides an effective API to retrieve precise data in real time




  • Hongxin Zhang
  • James Lindsay
  • Shane Neeley
  • Ryan Smith