Contributor
Jiahuang Lin

Human history and genome evolution project proposal


Mentors
Aaron Ragsdale, Simon Gravel
Organization
Canadian Center for Computational Genomics

There has been a recent surge in the development of open-source computational methods for simulating human evolution and analyzing human genome data. These provide many new opportunities for genomic research, but the integration of these different resources is currently poor. In particular, turning models of human history into evolutionary models is notoriously time-consuming and bug-prone, and it requires knowledge of the specifics of each simulation tool. The major goals of this project are to develop a library of widely used historical models that integrate across multiple simulation tools, and to develop more robust and user-friendly model specification tools to automate the workflow of genomic and evolutionary analyses.