Canadian Centre for Computational Genomics

Analytical solutions for Next-Generation Sequencing data

Technologies
python, javascript, react, nodejs, r-project
Topics
visualization, bioinformatics, web development, data science, statistics
Analytical solutions for Next-Generation Sequencing data

The Montreal C3G node is hosted at the McGill University and Genome Quebec Innovation Centre. The Montreal node is strongly involved with GenAP and has developed several genomic data analysis pipelines. Since 2011, we have completed more than 400 bioinformatics analysis projects with over 290 distinct groups of researchers across Canada. Our teams have significant experience in personalized medicine applications. These have included genome analysis and interpretation of personal genomes, technology and services to record patient presentations, RNA- and ChIP-seq data analysis, and analysis of complete human epigenomes in both germline disorders and cancers. Each year C3G co-organizes several international workshops about next-generation sequencing data analysis.

The Montreal C3G node develops the GenPipes pipelines which consist of Python scripts which create a list of jobs running Bash commands to analyze NGS data. Those scripts support dependencies between jobs and a smart restart mechanism if some jobs fail during pipeline execution. Job commands and parameters can be modified through several configuration files. We currently maintain 7 pipelines and develop 3 others.

The Montreal C3G node also develops several bionformatics tools:

2020 Program

Successful Projects

Contributor
Harshit Maheshwari
Mentor
Simon Chénard, David
Organization
Canadian Centre for Computational Genomics
Ingesting the Canadian Common CV
The Canadian Common CV (CCV) is a tool that allows Canadian researchers to input their resume in a standardized format. It is used by multiple...
Contributor
Mohd Arshul Mansoori
Mentor
P-O, Edouard Henrion
Organization
Canadian Centre for Computational Genomics
DevOps for GenPipes
DevOps for GenPipes would create an automatic deployment of the GenPipes project in the cloud using Terraform. It would support multiple cloud...
Contributor
Andjela Todorovic
Mentor
Ivan Krukov, Simon Gravel
Organization
Canadian Centre for Computational Genomics
Large-scale modeling of genetic data
The objective of the problem arises from the reconstruction of gene genealogies problem - from a given genotypes of sequence data from contemporary...
Contributor
Konstantinos Kyriakidis
Mentor
Jose Hector Galvez
Organization
Canadian Centre for Computational Genomics
Development of a Long-read Nanopore RNA-seq pipeline in GenPipes
The majority of contemporary genomics and transcriptomics research is carried out using short-read technology such as the output of Illumina...
Contributor
Moonshroom
Mentor
P-O, Edouard Henrion
Organization
Canadian Centre for Computational Genomics
Automatic update of the C3G software stack catalog
GenPipes is an important tool by C3G. GenPipes contains a suite of different software. The software contained in the suite is continuously updated...