Contributor
Sindhu Kandepu

Multi-model approach for discovery of associations between gene variants and diseases.


Mentors
Tim Jackson
Organization
Global Alliance for Genomics and Health
Technologies
python, postgresql, tensorflow
Topics
machine learning, Computational Genomics
To identify possible relations between gene variants, phenotypes, and diseases - an ideal way would be a multi-model approach that involves: • Supervised learning methods to discover diseases associated with combinations of gene variants and clinical features. • Also unsupervised learning methods like clustering to understand the underlying patterns among diseases that went unnoticed before. This could be a strong evidence-based approach for clinical treatments.